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Critical Technology

Advanced Therapeutics, Vaccines & Medical Countermeasures

The capacity to develop and field advanced therapeutics, vaccines and medical countermeasures, new modalities, antimicrobials, and the development-at-speed capability that pandemics and biological threats demand. One of the capabilities of Biotechnology & Health Technologies.

International families
76k2015 to 2024
Leading country
United States3.2× the next
All families
134khome filings included
Over five years
Rising2020 to 2024 against the five before

Year by year

Patent families by country of origin and the year of the earliest filing, 2000 to 2025; 2025 is a part year, still filling in. International families are those for which protection was sought beyond one country.

Volume

International patent families in the capability, by the year of the earliest filing.

Source: Global Institute for National Capability (GINC), 2026. Underlying patents from 107 patent offices, IFI CLAIMS and Google

Share by country

Each country's share of the year's international families, in per cent: the capability's five largest countries of origin, 2015 to 2024, and the rest of the world.

Source: Global Institute for National Capability (GINC), 2026. Underlying patents from 107 patent offices, IFI CLAIMS and Google

Country leaderboard

International patent families, 2015 to 2024, by country of origin. Growth compares the latest five full years with the five before.

Ten largest

United States

China

Japan

South Korea

Germany

United Kingdom

France

Switzerland

Canada

Netherlands

35,382

11,223

4,471

4,072

2,767

2,633

2,265

2,190

1,273

962

2000 to 2025
1United States35,38246.5%1.3×
41,041
2China11,22314.7%3.2×
54,255
3Japan4,4715.9%1.1×
5,997
4South Korea4,0725.3%1.4×
7,989
5Germany2,7673.6%1.1×
2,981
6United Kingdom2,6333.5%1.1×
2,830
7France2,2653.0%1.0×
2,395
8Switzerland2,1902.9%1.0×
2,330
9Canada1,2731.7%1.2×
1,419
10Netherlands9621.3%1.2×
1,013
11Belgium9451.2%1.1×
992
12Israel8171.1%1.1×
879
13Australia7831.0%1.1×
826
14Taiwan7281.0%1.1×
1,056
15Sweden5800.8%1.5×
619
16Denmark5750.8%1.3×
627
17Spain5660.7%1.5×
611
18Italy5550.7%1.3×
614
19Singapore5340.7%1.7×
560
20India4330.6%1.5×
479
21Ireland3550.5%0.8×
382
22Russia2120.3%1.1×
949
23Norway1740.2%1.0×
184
24Austria1680.2%1.1×
175
25Türkiye1390.2%1.9×
209
26Brazil1230.2%1.1×
335
27Poland980.1%1.5×
190
28Finland960.1%1.1×
101
29Portugal950.1%1.1×
103
30Cayman Islands920.1%0.7×
118
31Hong Kong680.1%2.6×
102
32Czechia540.1%1.2×
68
33Mexico500.1%0.7×
147
34New Zealand410.1%0.9×
49
35Luxembourg390.1%0.2×
42
36South Africa350.0%0.9×
38
37Hungary320.0%1.5×
44
38Malaysia210.0%0.3×
44
39Saudi Arabia150.0%1.1×
44
40Liechtenstein50.0%0.3×
5

Applicants

The largest applicants by international patent families, 2015 to 2024: across the world, then within each of the five countries with the most families in Advanced Therapeutics, Vaccines & Medical Countermeasures. Names are as held in the source and are not consolidated across subsidiaries.

Global

76,135 international families

UNIV CALIFORNIA · United States

INST NAT SANTE RECH MED · France

HOFFMANN LA ROCHE · Switzerland

UNIV TEXAS · United States

REGENERON PHARMA · United States

UNIV LELAND STANFORD JUNIOR · United States

1,233

992

769

696

685

585

United States

35,382 international families

UNIV CALIFORNIA

UNIV TEXAS

REGENERON PHARMA

UNIV LELAND STANFORD JUNIOR

UNIV PENNSYLVANIA

US HEALTH

1,215

672

665

572

532

472

China

11,223 international families

JIANGSU HENGRUI MEDICINE CO

Shanghai hengrui pharmaceutical co ltd

JIANGSU HENGRUI PHARMACEUTICALS CO LTD

INNOVENT BIOLOGICS SUZHOU CO LTD

SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD

BIO THERA SOLUTIONS LTD

207

168

166

123

111

101

Japan

4,471 international families

UNIV OSAKA

UNIV TOKYO

CHUGAI PHARMACEUTICAL CO LTD

UNIV KYOTO

TAKEDA PHARMACEUTICALS CO

DAIICHI SANKYO CO LTD

221

211

198

176

154

153

South Korea

4,072 international families

SEOUL NAT UNIV R&DB FOUNDATION

UNIV KOREA RES & BUS FOUND

UNIV YONSEI IACF

KOREA ADVANCED INST SCI & TECH

KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY

CATHOLIC UNIV KOREA IND ACADEMIC COOPERATION FOUNDATION

207

102

102

101

83

81

Germany

2,767 international families

BioNTech SE

BOEHRINGER INGELHEIM INT

IMMATICS BIOTECHNOLOGIES GMBH

MERCK PATENT GMBH

DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS

DEUTSCHES KREBSFORSCH

221

140

125

97

72

69

Similar capabilities

The nine capabilities that share the most international patent families with Advanced Therapeutics, Vaccines & Medical Countermeasures, 2015 to 2024: the families counted in both as a share of those counted in either. Each card shows its five largest countries.

Critical Technology

Synthetic Biology & Genetic Engineering

36.4% shared · 40,220 families in both

United States

China

Japan

South Korea

Germany

31,378

14,103

6,820

3,970

2,703

Human Capital

Physical Health & Longevity

34.5% shared · 72,198 families in both

United States

China

South Korea

Japan

Germany

77,497

32,383

14,190

14,101

7,671

Critical Technology

Biomanufacturing

20.1% shared · 24,652 families in both

United States

China

Japan

South Korea

Germany

25,142

10,048

9,595

4,747

3,497

Human Capital

Nutrition & Preventive Health

10.6% shared · 10,290 families in both

United States

South Korea

China

Japan

Switzerland

7,952

5,251

3,446

3,403

1,203

Critical Technology

Genomics & Biological Data

5.2% shared · 5,758 families in both

United States

China

Japan

South Korea

Germany

17,818

5,444

3,003

2,851

1,616

Human Capital

Public Health Functions

4.3% shared · 3,706 families in both

United States

China

Japan

South Korea

Germany

5,511

1,782

1,627

909

600

Strategic Infrastructure

Public Health & Laboratories

3.3% shared · 3,080 families in both

United States

Japan

China

Germany

South Korea

7,163

3,632

2,667

1,475

1,202

Critical Technology

Nuclear Medicine & Radioisotope Technologies

2.2% shared · 1,911 families in both

United States

China

Japan

Germany

South Korea

4,153

2,013

1,410

792

720

Production & Innovation

Agrifood & Primary Production

2.1% shared · 4,278 families in both

United States

Japan

China

Germany

South Korea

28,708

17,669

15,613

10,229

9,737

Crosswalk

How Advanced Therapeutics, Vaccines & Medical Countermeasures is matched to the patent classifications. The entries below were chosen for it; each stands for itself and everything beneath it in the scheme, 638 Cooperative entries in all. A patent family counts when any of its codes, in either scheme and at any office, falls under one of them. Codes since retired are placed under the entries that replaced them.

EntryTitle in the schemeWhy it is chosenCPC codesIPC codesDocuments
A61K39/00Medicinal preparations containing antigens or antibodiesVaccines and antibody medicines376682,481,082
C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodiesAntibodies157591,512,140
A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapyGene therapy121287,790
A61K40/00Cellular immunotherapyCellular immunotherapy13426442,425
A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytesLymphocyte and T-cell therapies1150,794
A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cellsStem cell therapies1144,147
A61K35/76Viruses; Subviral particles; BacteriophagesTherapeutic viruses and bacteriophages6677,092
A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragmentAntibody-drug conjugates551347,148
A61K31/7088Compounds having three or more nucleosides or nucleotidesNucleic acid medicines, including RNA therapeutics77208,959

CPC and IPC codes are the codes in use on patent documents, at any office, that fall under the entry. Documents is the larger of the two schemes' counts of documents carrying one of them. An entry with no IPC codes can be told apart only in the Cooperative scheme.

The Cooperative codes in use that count towards Advanced Therapeutics, Vaccines & Medical Countermeasures: 749 codes on 5,398,075 documents. The 150 most used are listed; the full list is in the cpc-to-capability.csv download.

CodeTitleUnder entryHow placedDocuments
A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodiesA61K39/00In the scheme369,886
A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serumA61K39/00In the scheme140,787
A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapyA61K48/00In the scheme137,869
A61K39/00Medicinal preparations containing antigens or antibodiesA61K39/00In the scheme132,546
C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humansC07K16/00In the scheme120,544
A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokinesA61K39/00In the scheme115,003
A61K39/12Viral antigensA61K39/00In the scheme114,170
C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinantsC07K16/00In the scheme99,219
A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration scheduleA61K39/00In the scheme88,876
A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cellsA61K40/00In the scheme85,541
C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodiesC07K16/00In the scheme81,754
C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamilyC07K16/00In the scheme77,103
C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cellsC07K16/00In the scheme72,922
A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvantsA61K39/00In the scheme70,983
A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigensA61K39/00In the scheme59,978
C07K16/2818Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152C07K16/00In the scheme59,968
A61K31/7088Compounds having three or more nucleosides or nucleotidesA61K31/7088In the scheme58,635
A61K31/713Double-stranded nucleic acids or oligonucleotidesA61K31/7088In the scheme57,643
C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymesC07K16/00In the scheme56,544
A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid deliveredA61K48/00In the scheme55,022
C07K16/2863Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulatorsC07K16/00In the scheme53,474
A61K47/6849Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinantA61K47/68In the scheme52,721
A61K2039/53DNA (RNA) vaccinationA61K39/00In the scheme52,464
A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytesA61K35/17In the scheme50,794
A61K40/31Chimeric antigen receptors [CAR]A61K40/00In the scheme50,750
A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administrationA61K39/00In the scheme48,676
C07K16/22Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulatorsC07K16/00In the scheme47,863
A61K39/0011Cancer antigensA61K39/00In the scheme47,219
C07K16/32Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenesC07K16/00In the scheme47,136
A61K2039/507Comprising a combination of two or more separate antibodiesA61K39/00In the scheme45,520
C07K16/2896Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhereC07K16/00In the scheme44,486
A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cellsA61K35/28In the scheme44,147
C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferonsC07K16/00In the scheme43,244
C07K16/2809Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complexC07K16/00In the scheme43,121
C07K16/2878Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95C07K16/00In the scheme40,486
C07K16/2827Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86C07K16/00In the scheme39,995
A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester linksA61K31/7088In the scheme39,887
A61K2039/70Multivalent vaccineA61K39/00In the scheme36,357
A61K2039/552Veterinary vaccineA61K39/00In the scheme32,703
A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cellA61K47/68In the scheme31,333
A61K2039/55505Inorganic adjuvantsA61K39/00In the scheme30,609
A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; PolymersA61K39/00In the scheme30,055
A61K40/42Cancer antigensA61K40/00In the scheme29,160
A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugatesA61K47/68In the scheme28,682
C07K16/244Interleukins [IL]C07K16/00In the scheme27,734
C07K16/2887Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20C07K16/00In the scheme27,228
A61K47/6889Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environmentA61K47/68In the scheme26,510
A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59A61K39/00In the scheme26,328
C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodiesC07K16/00In the scheme25,286
A61K2039/5256Virus expressing foreign proteinsA61K39/00In the scheme24,733
A61K39/145Orthomyxoviridae, e.g. influenza virusA61K39/00In the scheme24,057
A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2A61K39/00In the scheme23,040
A61K2039/5254Virus avirulent or attenuatedA61K39/00In the scheme22,652
A61K39/39591Stabilisation, fragmentationA61K39/00In the scheme22,480
A61K40/4211CD19 or B4A61K40/00In the scheme22,310
A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral responseA61K39/00In the scheme22,154
C07K16/44Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acidsC07K16/00In the scheme21,979
C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferonsC07K16/00In the scheme21,387
A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic responseA61K39/00In the scheme21,257
A61K39/385Haptens or antigens, bound to carriersA61K39/00In the scheme21,206
C07K16/241Tumor Necrosis FactorsC07K16/00In the scheme21,126
A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragmentA61K47/68In the scheme18,579
A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvantsA61K39/00In the scheme18,553
A61K40/32T-cell receptors [TCR]A61K40/00In the scheme18,373
A61K48/0058Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contructA61K48/00In the scheme18,155
C07K16/46Hybrid immunoglobulinsC07K16/00In the scheme17,869
A61K2039/5252Virus inactivated (killed)A61K39/00In the scheme17,819
A61K48/0075Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneousA61K48/00In the scheme17,473
A61K47/68031Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being an auristatinA61K47/68In the scheme17,405
A61K40/24Antigen-presenting cells [APC]A61K40/00In the scheme17,395
A61K2039/55511Organic adjuvantsA61K39/00In the scheme17,359
A61K2039/5158Antigen-pulsed cells, e.g. T-cellsA61K39/00In the scheme17,262
A61K2039/55516Proteins; PeptidesA61K39/00In the scheme16,268
A61K35/76Viruses; Subviral particles; BacteriophagesA61K35/76In the scheme16,120
A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]A61K39/00In the scheme15,680
A61K2039/5156Animal cells expressing foreign proteinsA61K39/00In the scheme15,440
A61K2039/5258Virus-like particlesA61K39/00In the scheme15,304
A61K40/15Natural-killer [NK] cells; Natural-killer T [NKT] cellsA61K40/00In the scheme15,276
A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cellsA61K39/00In the scheme15,249
A61K2039/585Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancerA61K39/00In the scheme15,160
C07K16/3069Reproductive system, e.g. ovaria, uterus, testes, prostateC07K16/00In the scheme15,101
C07K16/2875Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154C07K16/00In the scheme15,099
A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycinA61K47/68In the scheme14,913
A61K47/6855Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cellA61K47/68In the scheme14,243
A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodiesA61K39/00In the scheme13,761
C07K16/065Purification, fragmentationC07K16/00In the scheme13,426
A61K40/19Dendritic cellsA61K40/00In the scheme13,346
A61K2039/543Mucosal route intranasalA61K39/00In the scheme13,244
C07K16/2833Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-moleculesC07K16/00In the scheme13,236
C07K16/283Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64C07K16/00In the scheme13,081
A61K39/092StreptococcusA61K39/00In the scheme12,989
A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid AA61K39/00In the scheme12,934
A61K39/21Retroviridae, e.g. equine infectious anemia virusA61K39/00In the scheme12,911
C07K16/26Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factorsC07K16/00In the scheme12,691
A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester linksA61K31/7088In the scheme12,583
A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-toleranceA61K39/00In the scheme12,547
A61K40/22Immunosuppressive or immunotolerisingA61K40/00In the scheme12,007
A61K48/0041Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymericA61K48/00In the scheme11,874
A61K48/0008Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the compositionA61K48/00In the scheme11,860
A61K40/46Viral antigensA61K40/00In the scheme11,843
A61K2039/542Mucosal route oral/gastrointestinalA61K39/00In the scheme11,754
C07K16/2851Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72C07K16/00In the scheme11,599
A61K31/7125Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiestersA61K31/7088In the scheme11,581
A61K2039/55577Saponins; Quil A; QS21; ISCOMSA61K39/00In the scheme11,394
A61K48/0066Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acidA61K48/00In the scheme11,210
C07K16/10RNA virusesC07K16/00In the scheme10,808
A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuatedA61K39/00In the scheme10,687
A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animalsA61K39/00In the scheme10,609
A61K39/215Coronaviridae, e.g. avian infectious bronchitis virusA61K39/00In the scheme10,563
A61K39/0005Vertebrate antigensA61K39/00In the scheme10,341
A61K47/68033Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a maytansineA61K47/68In the scheme10,329
C07K16/3061Blood cellsC07K16/00In the scheme10,195
A61K39/095NeisseriaA61K39/00In the scheme10,034
A61K39/02Bacterial antigensA61K39/00In the scheme9,705
A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophagesA61K39/00In the scheme9,703
C07K16/303Liver or PancreasC07K16/00In the scheme9,702
A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteinsA61K39/00In the scheme9,494
A61K2039/6031ProteinsA61K39/00In the scheme9,377
A61K39/35AllergensA61K39/00In the scheme9,369
A61K2039/55522Cytokines; Lymphokines; InterferonsA61K39/00In the scheme9,295
A61K40/10Cellular immunotherapy characterised by the cell type usedA61K40/00In the scheme9,174
A61K39/08Clostridium, e.g. Clostridium tetaniA61K39/00In the scheme9,124
A61K40/4202Receptors, cell surface antigens or cell surface determinantsA61K40/00In the scheme9,115
A61K47/68037Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a camptothecin [CPT] or derivativesA61K47/68In the scheme9,057
C07K16/3015BreastC07K16/00In the scheme9,034
A61K39/245Herpetoviridae, e.g. herpes simplex virusA61K39/00In the scheme8,850
C07K16/36Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factorsC07K16/00In the scheme8,733
C07K16/3046Stomach, IntestinesC07K16/00In the scheme8,684
A61K31/712Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyriboseA61K31/7088In the scheme8,491
A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosisA61K39/00In the scheme8,419
A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viralA61K39/00In the scheme8,338
A61K2039/525VirusA61K39/00In the scheme8,316
A61K35/761AdenovirusA61K35/76In the scheme8,167
A61K39/155Paramyxoviridae, e.g. parainfluenza virusA61K39/00In the scheme8,164
C07K16/005Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage librariesC07K16/00In the scheme7,944
A61K40/4215Receptors for tumor necrosis factors [TNF], e.g. lymphotoxin receptor [LTR], CD30A61K40/00In the scheme7,823
A61K47/6817ToxinsA61K47/68In the scheme7,767
C07K16/3023LungC07K16/00In the scheme7,756
A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; HaemophilusA61K39/00In the scheme7,640
A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)A61K39/00In the scheme7,637
C07K16/3007Carcino-embryonic AntigensC07K16/00In the scheme7,496
A61K40/416Antigens related to auto-immune diseases; Preparations to induce self-toleranceA61K40/00In the scheme7,478
A61K31/7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymineA61K31/7088In the scheme7,334
C07K16/2869Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptorsC07K16/00In the scheme7,332
A61K40/421Immunoglobulin superfamilyA61K40/00In the scheme7,238
A61K2039/627Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linkerA61K39/00In the scheme7,211
C07K16/3053Skin, nerves, brainC07K16/00In the scheme7,121
A61K48/0033Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being non-polymericA61K48/00In the scheme7,119
C07K16/1145Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding siteC07K16/00In the scheme7,107
A61K47/6809Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycinA61K47/68In the scheme7,026
Match: Direct
The capability is itself a technology or a kind of physical system, and the classification names it. Antimicrobials have no clean entry: the anti-infective activity tags (A61P31) are too broad and include traditional remedies, so they are left out. The crosswalk is a first pass that nobody has reviewed.

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